APOCYNIN, +99% pure, white powder, ANTI-AGING, Immune System Booster/Restorer

Description: -- Our 10g size is $20 + $4.10 shipping,,, via 'USPS Ground Advantage' service (which includes tracking and up to $100 insurance).-- Our 25g size is $37 + $4.10 shipping,,, via that same USPS service with the included tracking & insurance. NOTE : In our listing for Apocynin we try to present readers with accurate, balanced, understandable information. In explaining what the research indicates this plant-based substance can do, we are equally careful to explain what it probably can not do. We give you the info and then let you decide. You will receive our Apocynin exactly as described and shown in our photos. We have hundreds of very satisfied customers. We earn our continued excellent Ebay rating every day, with every transaction. ------------------------------------------------------------------------- APOCYNIN is a natural plant substance that acts as an ANTI-AGING agent, in several ways: -- As detailed below, it can be dissolved in water and applied to skin as an inexpensive topical solution, or it can be added to skin creams in very small amounts. Research has shown that Apocynin supports improved function of aging stem cells in skin tissue, thus maintaining or increasing production of fresh skin cells. -- When taken orally, It has potent ANTI-OXIDANT & IMMUNE-REGULATORY properties. It is a safe and effective "NADPH-Oxidase inhibitor". -- Apocynin can help balance the immune system’s response to severe bacterial, fungal or viral infections which can produce overwhelming levels of inflammation. -- It is also shown to be effective in helping reduce levels of chronic, low-level inflammation, --such as the type that can s-l-o-w-l-y develop over time in the body and the brains of the elderly. -- Hygienic, clean, fine white powder with a faint vanilla odor . CAS 498-02-2. Acetovanillone. Exp. Date: May 18, 2025. -- We enclose a small spoon/scoop with a level volume of 0.25 cc, for you to approximately measure small amounts. See our photos. Note: A sensitive 'milligram'-type scale (obtained elsewhere) will allow more accurate measurements. -- We include an accurate, up-to-date Certificate of Analysis matched with each Order we send out. -- We ship to all 50 USA states only. WE SHIP FAST !! NOTE: USPS raised the postal rates for "Ground Advantage Service" by 5.4% on Jan. 21, 2024. We have therefore raised our Flat Rate shipping fee by that same percentage, from the former $3.90 to the current $4.10. -- Your shipment will consist of the following: - APOCYNIN in small, re-sealable, heavy duty (4 mil) zip-closure plastic bag(s) containing the 10g, or 25g amount(s) you ordered. - A 0.25 cc spoon/scoop for approximately measuring small amounts of the Apocynin (see our PHOTOs). - An up-to-date Certificate of Analysis (COA) specific to your item shipped. - The above items are shipped in a 6 inch x 7 inch soft, bubble-cushioned poly mailing envelope. We stress cleanliness and purity. We have never allowed returns of our Apocynin, because we cannot allow the possibility of receiving a returned item that is less pure, or less clean, or is any way different than when we shipped it. We cannot resell returned items, because this would represent a potential risk to our other customers. Our description below is very detailed, providing clear and exact information about the white, high-purity Apocynin we sell. We will quickly ship it to you exactly as described, and as seen in our photos,,, no mistakes or surprises. ************************************************************************************************************************* APOCYNIN HISTORY (APOCYNIN pronunciation,,, it sort of sounds like the word OPOSSUM,,, a - POS’- i -nin ) In the book “Positive Medical Agents” by the American Chemical Institute, published in 1854 by B. Keith & Co., page 108 mentions “Apocynin” root having long been used by native Americans prior to the arrival of Europeans, so its use as a medicinal herb in North America dates back many centuries. As of 1883, it was becoming studied more closely as an impure substance extracted from the roots of certain small plants that grow in Northern US and Canada. About 8 years later, a chemist named Otto figured out how to synthesize Apocynin in the lab, but scientists of that time had their doubts about whether the laboratory version was truly the same as the plant-derived version. In 1908, an English chemist (Finnemore) decided to find the answer. He obtained 40 Kg of the plant roots and after great time & effort, he extracted 80 grams of pure Apocynin from it. (40,000 grams yielded only 80g of the Apocynin,,,a very low 0.2% yield.) Reference: Journal, Chemical Society of London, Vol.93, part 2, pp.1513-19. The Englishman then performed exhaustive tests that proved the laboratory-made Apocynin is identical in every physical, medical and biochemical way to the Apocynin that occurs naturally. This forever ended the debate. Crystals of high-purity Apocynin are colorless and become a white or off-white powder when finely ground. Apocynin has a faint vanilla-like odor, owing to the fact that it's in the same chemical 'family' as Vanilla. In fact, it is a natural component of common Vanilla extract that is used in cooking. Our 99.9% pure Apocynin meets (or even exceeds) the level of purity typically used for medical laboratory research (including the April 3, 2019 skin research referenced below), at a price that is very reasonable. In the years after Finnemore’s 1908 investigation, Apocynin became increasingly recognized for its ability to help reduce inflammation in joints, connective tissues, the circulatory system and the liver. In 1971, it was discovered to also be present in the yellow roots of a Himalayan plant (Picrorhiza kurroa *) long used in the Ayurvedic medical tradition as a ‘liver tonic’ and a general healing substance, in Nepal. By the 1990’s, Apocynin was capturing the interest of mainstream Science, and researchers began studying it more intensively. In 2008, a scientific review of its ‘molecular aptitudes’ was published. In that review, it was found to have an ‘aptitude’ for being beneficial in treating an extremely wide array of medical conditions. It has the title, "Apocynin: Molecular Aptitudes". You can copy and paste the following underlined link into your web browser, then click the article. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593395/ Once on this US Gov’t website, you could also enter the word “APOCYNIN” into the search box seen at the top and be presented with hundreds of additional research publications, right up to the present time. If you click the word "Advanced Search" seen in blue text beneath the search box, you will be presented with ways you can narrow your search to whichever medical aspects of Apocynin interest you the most, such as "Apocynin + Inflammation", etc. Over the past 25 years or so, Science has been developing powerful new tools & methods for delving ever deeper into the way cells work at the level of individual genes, proteins and molecules. By 2012, researchers were beginning to get indications that Apocynin has the ability to somehow stimulate or revitalize under-performing stem cells, -those special cells that keep us going. Stem cells have the unique ability to make fresh new replacements for old cells that are wearing out. Over time, our stem cells start getting worn out too, and we begin exhibiting the tell-tale signs of aging. How does Apocynin work ? Scientific & medical information often contains terminology that may be unfamiliar to many people. What follows is an attempt to explain the relevant Science in terms that are hopefully a little more understandable,,, Apocynin can be taken orally in small amounts, and/or it can be applied topically. If taken orally, it has the ability to keep the immune system properly regulated. If applied topically, scientists have recently discovered that it can actually restore stem cells in the deepest layers of skin tissue. MEDICINAL PROPERTIES OF APOCYNIN TAKEN ORALLY Let's start with a little background about our immune systems. White blood cells circulating in our blood are our 1st line of defense against infection. There are several types of them, --most prominent are the neutrophils and the macrophages. When white blood cells encounter a 'bad' invasive cell (such as a fungus, bacteria or virus) they perform some chemical tricks involving oxygen, enlisting the oxygen to help them attack the invasive foreign cell. In a way, Oxygen has a split personality. An individual oxygen atom does not like to be alone. It is chemically ‘aggressive’. It wants to join/react with things around it. Fortunately, when two individual oxygen atoms join together, they stabilize each other by forming a molecule of the life-sustaining oxygen that we all breathe. So, a single oxygen atom is ‘hyper’, but two of them joined together into a molecule are ‘calmer’. Our immune system takes advantage of this “split personality” of oxygen, and employs several methods to revert it's calm version into its aggressive, reactive “hyper” version, to fight infection. The advance guard of our immune systems are the specialized, infection-fighting white blood cells called macrophages. Each patrolling macrophage contains an enzyme called “NADPH oxidase”. If a macrophage senses a foreign invader (such as a harmful virus, bacteria or fungus), the NADPH oxidase within it will instantly trigger the production of SUPEROXIDE, --a specialized molecule that is armed with the ‘aggressive’ version of oxygen that wants to react with something. You could visualize this immune response as being akin to a patrolman who wakes up and releases a specialized type of ‘attack dog’. (We’ll discuss more about superoxide, below.) It is important to understand that, in attacking the invader, that 'attack dog' (a macrophage or some other type of white blood cell) is also creating a certain level of inflammation. The larger the number of white blood cells that become present to attack an invader, the larger the amount of inflammation that occurs. If an entire army of white blood cells get called into action, this large response can unintentionally result in levels of inflammation that are harmful. This is where Apocynin can step in to help keep things more balanced. When invading pathogen cells (fungus, bacteria, virus) become spotted and attacked by the "advance guard" macrophages, the macrophages release small protein molecules called cytokines, which signal the more-common variety of white blood cells (neutrophils) to join the attack. If the pathogen cells are rapidly multiplying, our various white blood cells release even more amounts of cytokines, signaling even more of their fellow white blood cells to join the fray. In the face of an overwhelming infection, the immune system response can escalate into a very serious medical condition known as a "cytokine storm". APOCYNIN can help prevent things from ever reaching this point. It is able to help regulate & balance the immune system’s response to a serious infection. This allows the immune system to maintain its maximum effectiveness in a drastic situation. ------------------------------------------------ SUPEROXIDE : THE IMMUNE-SYSTEM'S DOUBLE-SIDED SWORD TO FIGHT INFECTION Apocynin can be very effective in supporting control of ‘everyday’, low-level inflammatory conditions. We've already mentioned the way our macrophages utilize the 'split personality' of oxygen, by converting its 'calm' molecular form into a 'hyper' armed form (called superoxide), able to attack invading pathogens. Superoxide is essential for keeping us alive! It is perhaps the immune system’s favorite ‘attack’ molecule for destroying invasive pathogens. Although our macrophages happen to employ the superoxide molecule, our immune system also has others in its toolbox. As a group, these type of oxygen-charged ‘attack’ molecules are called a “reactive oxygen species” (ROS). There are many varieties of ROS. They all need to be carefully guided and controlled so that, once unleashed, they attack only the intended target. Unfortunately, the passage of time leaves our aging bodies less able to guide the activity of superoxide and the other ROS substances. With less guidance, those substances can begin inflicting low-level ‘collateral damage’ on healthy cells and tissues. This process is so gradual that it can go unnoticed for years, --until it finally progresses to the point that symptoms of inflammation start becoming expressed in the body,,, and the brain. Scientists recognize Apocynin to be a very potent and very selective “NADPH oxidase inhibitor”. It has the selectivity needed to allow the immune system to regain better control of its ROS family of ‘attack molecules’, while not interfering with their ability to attack an invading pathogen. Operating at the cellular level, Apocynin can help keep our immune system better regulated. By doing so, it is able to help control the slow, insidious development of age-related inflammation in body & brain. For much more on this, you can read an excellent scientific article published on March 19, 2021 by a researcher named Dr. Felice Bedford, of the Univ. of Arizona. Just copy/paste the words “ Blocking Superoxide with Apocynin ” into your web browser. Once on that webpage, click the box at the top that says “OPEN PDF” to view the full, 14-page scientific article. The article is eye-opening. Apocynin is a very remarkable, and very multi-faceted, medicinal herb substance. Since Apocynin is great at keeping the “wild side” of oxygen well under control, it's also great at controlling another variety of ‘wild’ oxygen (called “free radicals”). Free radicals can be formed when incoming solar radiation (UV rays) whack into our cells the wrong way. And our cells (especially the mitochondria in their nuclei) can sometimes accidentally produce them on their own, in the course of going about their routine business. Fortunately, Apocynin is also a potent ANTI-OXIDANT. It is able to “quench” (snuff) free radicals before they can do harm within our bodies. Apocynin can help keep our cellular repair mechanisms and our immune system functioning properly, --and better controlled. Apocynin is a small molecule that is able to cross the blood-brain barrier to reach the brain, where it can help reduce the slow, hidden deterioration of brain cells that is caused by the general aging process. Instead of dying, an old brain cell can hobble along in an inflamed state in which it is secreting substances that begin making neighboring brain cells become inflamed too. As this process continues to cascade to ever more cells, a point is reached where there is a noticeable --and progressive-- decline in overall brain functioning and cognitive abilities. Apocynin can help control the inflammation associated with this process. Apocynin reaches deep into the brain, where it can potentially give our brains better resistance to age-related cognitive decline. ---------------------------------------------- Apocynin is considered a safe medicinal substance when taken orally. In the USA, the FDA considers it to be a dietary / herbal supplement (not a drug) for which optimum human oral dosage levels have not yet been established. Thus, there is no “pharmaceutical” form of Apocynin recognized by the United States. (A foreign pharmaceutical manufacturer may describe it as such, but they are describing it in terms of the standards in their own country. Since the other country's standards can vary significantly from US FDA standards, they are not applicable here.) Although optimum human oral dosage levels have not been established, various studies involving laboratory animals have indicated that relatively low oral dosage levels of Apocynin are sufficient to produce effective results. When researchers are conducting tests to determine optimum oral dosage levels, they will often start with a lower daily dose. For example, they may start with a 50 mg dose, then gradually increase the daily dosage in small increments to determine a level where the best results are being achieved --without overdoing it. The easiest way to take a dose of our +99% pure Apocynin powder is to fill a standard shot glass about 3/4's full of very warm water. Then, using the tiny spoon we provide, measure out your desired amount of the Apocynin* and add it to the warm water. Stir it a few seconds and then quickly gulp it down before it can settle. Apocynin has the faint taste of Vanilla, and it will also produce a brief "tingling / numbing" sensation on your tongue for several seconds. *NOTE: If the tiny spoon is filled and then scraped level smooth, it will contain about 130mg of apocynin. When containing 100mg, it will be filled slightly less than level. SEE OUR PHOTOs. As vendors, FDA guidelines discourage us from providing any personal, one-on-one recommendations to individuals, regarding their own healthcare. We are unable to provide any specific, personal medical advice. Some people have reported feeling increased energy and endurance after taking an oral dose of 75-150mg Apocynin, but no scientific investigations have ever been conducted into this informally-reported effect. However, if taking an oral dose of Apocynin, it may be better to take it earlier in the day, instead of taking it near bedtime. ------------------------------------------------------------------------------------------------------------ ABOUT THE TOPICAL (SKIN) APPLICATION OF APOCYNIN On April 3, 2019 a group of Japanese researchers (Tokyo) announced their discovery that Apocynin can rejuvenate skin stem cells and maintain their continued activity. The 26-page scientific publication, with the title,,, 'Stem cell competition orchestrates skin homeostasis and ageing', was published in Nature. For a good 2-page summary of the Nature publication, do a web search for: "Anti-aging discovery could lead to restorative skin treatments", published in Scientific American, on April 4, 2019 (written by Dana Smith). In their April 3, 2019 publication, the researchers describe experiments in which they divided mice into three groups and then “wounded” them by surgically removing small, identical-sized areas of skin from their tails, --after having first established that the skin from a mouse tail is closely similar to human skin. They then applied solutions to the tail wounds in each group. (Let’s call them Groups A, B & C.) Group A’s wounds basically received a placebo solution (called a “vehicle” solution). Group B’s wounds received a solution containing a small amount of a synthetic lab-created substance called “Y-27632”. Group C’s wounds received a solution containing the nature-based Apocynin. As expected, the “vehicle” solution did very little. But they found that the Y-27632 solution and the Apocynin solution were each separately able to stimulate production of a vital skin protein called COLLAGEN 17. In Groups B and C, the wounds healed much better and faster, with much less scarring. In some ways, Y-27632 was superior to the Apocynin, but it is a rare research chemical that is not available to the public, and it is extremely expensive. Apocynin, a natural substance, came in a “close second”. It is an available, low-cost alternative to the lab-created Y-27632. They discovered that Apocynin increases your own body's production of COLLAGEN 17, which is the essential nutrient for the stems cells that create fresh skin cells. Thus, they had discovered a way to actually rejuvenate and maintain the deep, fundamental cellular activity & structure of the skin. Apocynin is functional,,, not a cosmetic! It can serve to create more ‘food’ for the skin stem cells and therefore help restore/maintain the actual foundation of the skin. To confirm the validity of the results observed in the tests they conducted with the skin of mice, they performed numerous ‘parallel’ tests with human skin cells grown in glass lab dishes. This produced very similar results, thus establishing that Apocynin (and Y-27632) can stimulate / restore increased stem cell activity in human skin. In the skin, the aging process causes a gradual breakdown of an intricate choreography that begins with a horizontal bottom ('basal') layer of stems cells that are always competing with each other, in a process that 'weeds out' the weaker stem cells. The healthiest stem cells are the ones that are getting the most nourishment by being firmly anchored to the bottom basal layer (i.e. the microscopic “basement floor” of our skin), where they keep producing fresh new skin cells. Those new cells then s-l-o-w-l-y develop and migrate up through various layers of our epidermis, until they reach our skin surface as adult skin cells to replace the ones that are always "flaking off" of us. Over time, such things as UVB sun radiation or the gradual accumulation of ‘free radical’ damage within our cells causes a depletion of Collagen 17, and this causes some skin stem cells to gradually begin 'losing their footing', instead of remaining firmly anchored to the ‘basement floor’ layer. This causes them to become less active, and they stop producing fresh skin cells. They can hang on in this weakened dormant state for quite a while, --still present, but also not producing new skin cells. At some point, those stem cells finally get completely detached. Once this happens, they are permanently lost. This slow and steady attrition of stem cells means our skin is producing less replacement skin cells. With the skin cell production line becoming progressively ‘undermanned’, our skin gradually develops the tell-tale signs of aging. The researchers discovered that Apocynin reinforces the health of the stem cells that were already still doing well. But more importantly, they found it can also restore many of those weaker 'borderline' stem cells that had been doing little more than taking up room,,, “sleeping on the production line”, so to speak. With those stem cells now ‘re-awakened’ and actively producing fresh skin cells again, the entire skin structure is fundamentally improved. Apocynin helps support the maintenance and the rejuvenation of stem cells in skin tissue. The following hypothetical example is intended to help explain some further details. But, if you are the sort of person who prefers to read all the exacting technical details, please read the full 26-page paper, referenced above. It is truly seminal, a very well-conceived and well-executed piece of research. Older persons will naturally have a greater population of weak, inactive stem cells than younger persons do. As a hypothetical illustration, let's say 15% of a 70-year-old person’s original skin stem cell population has been gradually, permanently lost over the years, never to return. And maybe another 15% of that person's skin stem cells have become that weak, inactive population that is still present, but not producing. At this point, the aging process may have effectively reduced his/her ability to produce fresh skin cells by 30% (15% gone forever + 15% inactive). Only 70% of the original stem cells are still producing fresh skin cells. Far too few fresh cells are now being produced to replace old, dying cells,,, and the effect becomes seen in the form of skin that is becoming thinner & more fragile, resulting in sagging skin, wrinkles, eye bags, age spots, slowed wound healing, more scarring, etc. In our example, the 70-year-old taking Apocynin for the first time can never replace the 15% of stem cells that had already been permanently lost forever. He/she got started too late to save those 15%. But thanks to the Japanese research group's discovery, we now know that Apocynin is able to restore Collagen 17 to levels where it can provide essential nourishment to the 70% of skin stem cells that were already healthy, and can keep them healthy. The Apocynin appears also able to re-awaken many of that other 15% of stem cells that had become non-productive, and can help keep them from lapsing back into inactivity again. They join the other 70% that had already still been productive, so now you have more stem cells making more fresh skin cells. By restoring the vital Collagen 17 levels, the Apocynin can make a significant difference and can help 'hold the line' against further skin aging. In this sense, Apocynin is therefore truly ANTI-AGING. Apocynin can reasonably be expected to need time to work. It can take several months for fresh 'newborn' skin cells to slowly migrate from the parent skin stem cells, journey up thru the epidermis layers, and finally make their arrival at the skin surface. While the Japanese skin research is certainly tantalizing, the extent of Apocynin's potential to actually make human skin appear "younger" is unknown at this point in time. It would be very unrealistic to expect Apocynin to suddenly reverse years of skin aging overnight to suddenly make you look years younger. However, the research seems to suggest that Apocynin does have the potential to slow the gradual appearance of further skin aging. This can be significant for anyone, but perhaps more significant the younger you are. If you are currently say age 45 and looking into the mirror some future day 25 years from now, you may be very glad that you started applying the inexpensive Apocynin skin solution way back in year 2024. You just may look appreciably younger than your fellow 70-yr-olds who are around you in year 2049. Hair follicles are another type of skin tissue, so it’s no surprise that some scientists (the stereotypical bald men with glasses?) have looked into its potential to restore hair. (Even older scientists can dream, right?) Unfortunately, the results were not encouraging, -at least not encouraging for older, long-bald individuals whose hair follicle stem cells became permanently lost long before this Apocynin discovery was ever made. You cannot restore a follicle stem cell that is no longer even present. But, this may not be the case for younger persons in whose scalps the dormant hair follicle stem cells may have just started to slow hair production (producing early signs of hair loss). Although dormant, those follicle stem cells are still physically present, so the research seems to indicate that at least some of them could be potentially recoverable. Regular topical applications of the aqueous Apocynin solution to the scalp could help support renewed activity of the dormant follicle stem cells. This could possibly slow further hair loss. Again, the Apocynin research was published fairly recently, and the aging process is very slow & gradual; there hasn’t yet been enough time to gauge what Apocynin can - or can not - do in this regard. It is worth noting that the same Japanese research group (and others) continue to investigate whether Apocynin can have beneficial effects on any other types stem cells found within our numerous organs and body systems. Given its safe low toxicity, its proven beneficial properties, and its relatively low cost,,, Apocynin would appear to be a sensible addition to a personal health regimen. MAKING THE TOPICAL SOLUTION : The April 3, 2019 publication says the Japanese researchers applied a 100 micromolar solution of Apocynin in phosphate-buffered saline solution (PBS) with an 0.5% wt/wt amount of DMSO added. (SEE OUR PHOTO of the formula, as published). In plainer terms, this is roughly equivalent to dissolving about 1 mg of Apocynin into two ounces of hot distilled water and then adding just one single drop of DMSO, and just 1mg of non-iodized table salt . At this low concentration, 10 grams ($20) of Apocynin would be sufficient to produce 156 gallons of the topical solution, at the strength they used. (1 gram = 1000 milligrams). (10 gram = 10,000 milligrams). This works out to only about 13 cents a gallon. At this low concentration, the distilled water would actually cost you more than the little speck of Apocynin that you are dissolving into it. NOTE : The single drop of pure DMSO per two ounces of solution is added to slightly increase skin permeability and allow the Apocynin to penetrate the skin just deeply enough to reach the layer of skin stem cells, and stay there. A larger amount of DMSO would just uselessly carry the Apocynin entirely thru your skin, and into your bloodstream. (In our experience, the German “Heiltropfin” brand of 99.5% DMSO is the most reliable. It is sold in small, brown glass bottles at an affordable price, and has a nice glass “pipette bulb” type of eyedropper built into the bottle’s screw lid.) In the Japanese research results, the beneficial skin effect is shown as being “dose dependent” (i.e. the higher the concentration, the greater the benefit). However, they did not describe having reached the point where they felt they had achieved an 'optimum solution concentration'. This leaves open the possibility that a slightly higher concentration could perhaps produce greater results. If a ‘stronger’ solution were to be desired, it would simply be a matter of dissolving a greater amount of Apocynin into the hot ‘water’. As an example, 10 mg could be dissolved into the 2 ounces, instead of just 1 mg. (Along with the same single drop of pure DMSO.) This would make a solution that is 10x’s more concentrated than used by the Japanese experimenters. If used at this higher concentration, 10 grams of Apocynin would be enough to make 15.6 gallons of the skin solution, and each single gram (a couple dollars’ worth) could produce 1.56 gallons of it (= 200 oz). The skin solution still remains very inexpensive. It is definitely worth looking into. Among our PHOTOs, you will see one that shows 100mg of Apocynin in the tiny measuring spoon, filled slightly less than level. (If the tiny spoon is filled level smooth, it will contain about 130 mg.) You will also notice another photo showing just 10mg in the same tiny spoon. As you can see, 10mg is a very small amount. If a person were to decide to make a solution that is 5x’s more concentrated than the Japanese group employed (instead of 10x’s), he/she could dissolve the 10mg Apocynin into 4 oz. of the hot distilled water, instead of 2 oz. water, thus diluting it. (Since you would now have 4 oz. of solution, you would now be using two drops of the pure DMSO, and 2mg of the salt.) NOTE #1: Although hot distilled water is used for preparing the skin solution, it must be allowed to cool to room temperature before being applied to the skin. NOTE #2 : If a person were considering applying a stronger Apocynin solution to his/her skin, it would be prudent to start by first applying it to some “test area” of the body that is less visible. Be sure that no adverse reaction is observed in the skin of the “test area” before applying the solution to the face. NOTE #3 : It may be convenient to transfer the Apocynin solution into some small 1 oz. spray bottles, such as the type used for applying a fine mist of perfume. For facial application, spray the clear, colorless mist into your palm to make a little puddle and then use your finger to dab it onto your face. This keeps it out of your eyes & nostrils. It dries rapidly, leaving no residue. Makeup can then be applied directly over it without interference. Store the prepared solution in the fridge, tightly capped, and make some fresh solution every couple weeks, instead of making a large batch of it and then letting it sit too long. If interested in adding our Apocynin powder to your own skin cream,,, ,,, it is best to first further pulverize our dry powder as finely as possible by placing perhaps just 10 to 20mg of it (SEE OUR PHOTO of 10mg Apocynin) onto a small glass plate and using the smooth ‘bottom’ of a metal spoon to grind it to maximum fineness. Then add a little bit of it to an ounce or two of the skin cream and stir it thoroughly. After several more stirs over the course of a couple days, it should gradually become completely dissolved into the cream. Thru a process of trial and error, you can determine for yourself the optimum amount of the finely-pulverized powder that can be stirred/dissolved into your particular skin cream, without leaving any undesired ‘graininess’. ----------------------------------------- DISCLAIMER: While the scientific information presented within our above Listing is accurate, the Listing and the statements within it have not yet been evaluated by the FDA. The information provided above is not intended to diagnose, treat, cure, or prevent any disease.

Price: 20 USD

Location: Philadelphia, Pennsylvania

End Time: 2024-03-13T06:49:04.000Z

Shipping Cost: 4.1 USD