Description: Discovering and Developing Molecules With Optimal Drug-Like Properties, Hardcover by Templeton, Allen C (EDT); Byrn, Stephen R. (EDT); Haskell, Roy J. (EDT); Prisinzano, Thomas E. (EDT), ISBN 1493913980, ISBN-13 9781493913985, Like New Used, Free shipping in the US
This authoritative volume provides a contemporary view on the latest research in molecules with optimal drug-like properties. It is a valuable source to access current best practices as well as new research techniques and strategies. Written by leading scientists in their fields, the text consists of fourteen chapters with an underlying theme of early collaborative opportunities between pharmaceutical and discovery sciences. Th explores the practical realities of performing physical pharmaceutical and biopharmaceutical research in the context of drug discovery with short timelines and low compound availability. Chapters cover strategies and tactics to enable discovery as well as predictive approaches to establish, understand and communicate risks in early development. It also examines the detection, characterization, and assessment of risks on the solid state properties of advanced discovery and early development candidates, highlighting the link between solid state properties and critical development parameters such as solubility and stability. Final chapters center on techniques to improve molecular solubilization and prevent precipitation, with particularly emphasis on linking physiochemical properties of molecules to formulation selection in preclinical and clinical settings.
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Book Title: Discovering and Developing Molecules With Optimal Drug-Like Prope
Item Length: 9.3in
Item Width: 6.1in
Author: Stephen R. Byrn
Publication Name: Discovering and Developing Molecules with Optimal Drug-Like Properties
Format: Hardcover
Language: English
Publisher: Springer New York
Publication Year: 2014
Series: Aaps Advances in the Pharmaceutical Sciences Ser.
Type: Textbook
Item Weight: 319 Oz
Number of Pages: Xi, 511 Pages
