Description: Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes.
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EAN: 9780128095522
UPC: 9780128095522
ISBN: 9780128095522
MPN: N/A
Item Length: 23.5 cm
Number of Pages: 392 Pages
Language: English
Publication Name: Epigenetic Mechanisms in Cancer: Volume 3
Publisher: Elsevier Science Publishing Co Inc
Publication Year: 2017
Subject: Biology
Item Height: 235 mm
Item Weight: 1000 g
Type: Textbook
Author: Sabita Saldanha
Subject Area: Bioengineering
Item Width: 191 mm
Format: Hardcover