Description: Mitochondrial DNA and Diseases Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Author(s): Hongzhi Sun, Xiangdong Wang Format: Paperback Publisher: Springer Verlag, Singapore, Singapore Imprint: Springer Verlag, Singapore ISBN-13: 9789811349294, 978-9811349294 Synopsis The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing. Authors made a great effort to overview roles of mtDNA signaling pathways, base excision repair, methylation, USP30-mediated regulation, mitochondrial ribosome, autophagy pathways, or ROS-dependent signaling in the pathogenesis, diagnosis, prevention and treatment of diseases. It also demonstrates the importance of basic mitochondrial genetics and the relationship between mutations and disease phenotypes and ageing. This book covers not only the basic information of mtDNA, the relationship of mtDNA and disease, but also mtDNA in stem cell and mitochondria and metabolism etc. The book is written for biological and clinical students and researchers in the field of mtDNA-associated diseases.
Price: 105.08 GBP
Location: Aldershot
End Time: 2024-09-22T11:45:44.000Z
Shipping Cost: 39.39 GBP
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Book Title: Mitochondrial DNA and Diseases
Item Height: 235 mm
Item Width: 155 mm
Series: Advances in Experimental Medicine and Biology
Author: Hongzhi Sun, Xiangdong Wang
Publication Name: Mitochondrial Dna and Diseases
Format: Paperback
Language: English
Publisher: Springer Verlag, Singapore
Subject: Biology
Publication Year: 2018
Type: Textbook
Item Weight: 503 g
Number of Pages: 230 Pages
