Rethinking Cancer: A New Paradigm for the Postgenomics Era by Bernhard Strauss (

Description: Rethinking Cancer by Bernhard Strauss, Marta Bertolaso Estimated delivery 4-14 business days Format Hardcover Condition Brand New Description "Steps toward an explanatory paradigm for cancer that integrates its different levels of organization (molecular, genetic, etc.) and also integrates theoretical and experimental biology with oncology"-- Publisher Description Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence.Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence.Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence.The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and non-coding DNA--the "dark matter" of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization. Author Biography Bernhard Strauss is Senior Research Associate at Cambridge University. Marta Bertolaso is Associate Professor of Philosophy of Science, Faculty of Engineering, University Campus Bio-Medico of Rome. Ingemar Ernberg leads the Ingemar Ernberg Group in the Department of Microbiology, Tumor, and Cell Biology at the Karolinska Institutet in Stockholm. Mina J. Bissell is Distinguished Scientist in the Biological Systems and Engineering Division at Lawrence Berkeley National Laboratory. Details ISBN 0262045214 ISBN-13 9780262045216 Title Rethinking Cancer Author Bernhard Strauss, Marta Bertolaso Format Hardcover Year 2021 Pages 376 Publisher MIT Press Ltd GE_Item_ID:131766191; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

Price: 78.15 USD

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End Time: 2024-10-26T03:37:28.000Z

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ISBN-13: 9780262045216

Book Title: Rethinking Cancer

Number of Pages: 432 Pages

Language: English

Publication Name: Rethinking Cancer : a New Paradigm for the Postgenomics Era

Publisher: MIT Press

Item Height: 1.1 in

Publication Year: 2021

Subject: Oncology, Internal Medicine, Life Sciences / Biology, Biomedical

Item Weight: 33.5 Oz

Type: Textbook

Item Length: 9.2 in

Author: Marta Bertolaso

Subject Area: Technology & Engineering, Science, Medical

Item Width: 7.2 in

Series: Vienna Series in Theoretical Biology Ser.

Format: Hardcover